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The Physician in the Pharmaceutical Industry

A career working for a major drug company is an alternative that is too often overlooked by physicians. Practicing physicians are needed by the research-based pharmaceutical industry in many areas, ranging from the pre-clinical screening of new drugs through the marketing of the FDA approved products.

Michael L. Carter, M.D., R.P.,
Assistant Director, Professional Services
Department, Roche Laboratories, A Div. of Hoffmann-La Roche Inc., Nutley, NJ

"There is a great future for physicians in the pharmaceutical industry. I am a physician who earned a Bachelor of Science degree in pharmacy before entering Hahnemann Medical College in 1974. After completing a residency program in internal medicine at Hahnemann, I practiced briefly in a public health clinic, then entered private practice. At the time, I had no idea those physicians other than those possessing a Ph.D., degree or who were already established, as research physicians were needed in the pharmaceutical industry.

After three years in private practice, I began to feel that there might be more to being a physician than clinical medicine alone could offer, so I began reading the ads for professionals for a hint of something more challenging. It was in an announcement in the Philadelphia Inquirer back in March of 1985 that I found that I was looking for: a well-known and well respected pharmaceutical manufacturer sought an Assistant Director of Medical Services, with experience in pediatrics, internal medicine, or family practice. The four or five key lines in that ad told me what I needed to know-that the pharmaceutical industry needed practicing physicians as well as research-oriented physicians.

The needs of the pharmaceutical industry are deceptively simple. Research-based drug firms need to collaborate and cooperate with leading clinical investigators to conduct well-controlled, state-of-the-art drug trials. An ongoing relationship with academicians and clinical consultants satisfies the immediate, short-term needs of the industry by providing second opinions on the uses of certain investigational and marketed drugs or on a drug development plan. Practicing physicians can also act as spoke persons to their peers concerning particular drugs or treatment approaches. Academic consultants, however, are important as medical educators for industry physicians, who are required to remain in touch with current trends in medical practice and who frequently arrange for clinical orientation programs.

On a long-term basis, the pharmaceutical industry has and always will require scientific and medical professionals to affirm the efficacy and safety of medications in the clinical research pipeline; to ensure the medical validity of scientific, educational, and promotional information; and to assess the medical impact of drugs proposed for licensing or for development through a New Drug Application (NDA).


Life Changes


The pharmaceutical industry has much to offer a physician it's more than just trading a stethoscope for a briefcase and a pen or a lab coat for a business suit. It's being a team player at all times and learning to access your creativity on demand. The rewards include opportunities for enrichment through continuing medical education programs; attendance at medical and scientific meetings; availability of textbooks and journal subscriptions as needed, and excursions to marketing and management meetings as part of the job. During the relatively short time I've been a member of the corporate community. I've had the honor of meeting and working with recognized experts in several medical specialties.

For me, all this has engendered somewhat of a difference life-style than I had become used to as a clinician. There have been predictable hours and dependable vacations even at times of year when I would previously have had to fight "tooth and nail" to get some free time. Although I have the opportunity to do so, I am no longer required to attend hospital rounds. I have also given up the dubious privilege of answering emergency calls. Also, regular pay is not something hard to get used to.

As a member of our Sales-Force Education Team, I'm often called upon to create a meaningful way of communicating medical concepts and rationales for treatment to our sales representatives. A recent presentation on anti-tumor antibiotics and their side effects, for example, could have been very uninteresting to this audience, which was largely untrained in the nuances of clinical medicine, but creativity allowed me to present this topic from the patient's viewpoint rather than the physician's. My Discussion took on meaning, as the representatives imagined what it would be like to be in a hospital bed, pulled away from family and friends, and receiving intravenous antibiotics because of fever and leucopenia, and oxygen because of pulmonary fibrosis. Because blood transfusions may also be required, I asked them to imagine the apprehension of a patient concerned about possibly acquiring the AIDS virus from blood replacement.

I completed the clinical picture by describing the side effects of treatment and their emotional impact on patients. I needn't tell you that the audience had had enough by this time, but the point was made. The presentation stimulated the audience to ask questions, enhanced their learning experience, and will be remembered better than a technical discussion in a medical text.


Difficult Choices

My decision to join the pharmaceutical industry was not made without soul-searching, however. A doctor's family is often the first to vocalize concerns and opinions about their young physician/family member looking for a place in the medical community; mine was no exception. I remember, for example, having to assure them that I would still be a physician in every sense of the word.

Frankly, one of my primary concerns was that, as a member of a large corporate community, I would lose any authority to make real medical decisions. I envisioned the corporate physician as an employee lost in a vast sea of other employees, chained to his desk, and involved in the development of potential products that might never reach the market - certainly not what Sinclair Lewis' young Doctor Arrowsmith had in mind. My personal experience in the drug development and marketing process has been exciting and rewarding, but one sobering fact for practicing physicians is that many members of the upper administrative echelons of industry arise not from the field o f medicine, but from business.

The pharmaceutical industry generally recruits practicing physicians by advertising career opportunities in leading newspapers and professional journals. Word-of-month, bulletin board postings at national meetings, and the use of executive recruiters also provide excellent candidates to fill industry positions. Although the executive recruiter is working for the pharmaceutical company seeking a physician, one enthusiastic about the credentials of a prospective candidate can often act as a coach in preparing him or her for a winning presentation at an interview. Once you're a member of the industry, further career mobility is possible within your firm if another position is more appealing.


Industry Roles for Physicians


Medical Marketing and Medical Services are two areas in which physicians are employed as full-time managers, but with an opportunity to use their medical skills. Physicians in these areas ensure that promotional and educational materials put out by the various parts of a firm's marketing division are medically valid and reflect current and accepted medical opinion. An industry physician also will assist in training the sales representatives and may be involved in conducting Phase IV drug studies.

In Research and Development, physicians generally are included throughout the drug development process, from Phase 0 (the pre-clinical evolution and screening of new compounds) to the comprehensive Phase III clinical trials conducted in support of an NDA. Industry physicians are then needed to provide to the Food and Drug Administrative and overall safety and efficacy evaluation and the medical rationale for approval as a new drug.
The physicians of the pharmaceutical industry also become part of the team responsible for ongoing safety surveillance and documentation of a drug's approved uses. These Phase IV studies and all drug safety studies of marketed drugs require a physician's direction.

Although referred to variously as a company's Medial Affairs, Professional Services, or Medical Services department, all are responsible for answering queries by health-care professional about a firm's products. Members of these departments are also asked to ensure the accuracy and appropriateness of product information and medial concepts used in the training of the sales force.


Attributes for Future Industry Physicians

How can you assess your own potential for a career in the pharmaceutical industry? I've listed below the "six P's of industry potential." We each have our individual strong points, so I did not rank these in any order of preference.
> Personality-A desirable candidate should be enthusiastic and must have the desire to work as part of a team. A physician graduating at the top of his class would be of little value to the industry if he is ill-equipped to deal effectively with non-medical peers, sales representatives, or the general public.
> Presentation-Written and verbal communication is among the cornerstones of a physician's effectiveness. Industry physicians spend a great deal of time representing their firms as scientific meetings, consultants' meetings, seminars, symposia, teleconferences, and in community service for the public.
> Prominence-You need not be well known, but physicians who have achieved some measure of distinction form their peers, either academically or in practice, are very desirable candidates for industry positions, particularly for the research area.
> Perceptiveness-Industry work requires an excellent knowledge of medicine, but perceptiveness drives the industry physician to anticipate the future needs of the health-care community and how a firm's products can best meet those needs. Foresight will help the industry-based physician direct an product team's efforts toward the best end.
> Prior Subspecialty Training-Although a specialty is important, further training in a subspecialty makes a physician all the more attractive and useful to the industry.
> Practice Experience-One aspect of medicine that has not changed since the day of Hippo craters is the experience of the senses. Medicine is learned and remembered through the bands, eyes, and ears. There is no substitute for first-hand application of the healing art.


Physicians are indeed in demand by the pharmaceutical industry. Industry continues to make a variety of career choices available for those earning an M.D. degree-choice offering the excellent remuneration and career benefits described above. Career advancement within the industry will result from the development of creative ability, administrative and management skills, and a willingness to become a team player. Finally, a position in the pharmaceutical industry allows the physician to use his or her medical skills in an environment conducive to predictable hours, infrequent job turnover, and the potential to help millions of patients at one time."


The Author: Michael L. Carter, MD., R.P.


Although he began his medical career in private practice, Dr. Carter later joined Hoffmann-La Roche, Inc., as Assistant Director of Professional Services at Roche Laboratories. After receiving his M.D. from Hahnemann Medical College, he completed his training in internal medicine at Hahnemann and at Crozer-Chester Medical Center in the Philadelphia area.

Article courtesy of: Resident & Staff Physician Vol. 35, No. 10

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